The smart Trick of stem cell treatment That Nobody is Discussing
With the concept a more rapid cell cycle is really a essential part of pluripotency, reprogramming efficiency might be improved. Methods for strengthening pluripotency via manipulation of cell cycle regulators involve: overexpression of Cyclin D/Cdk4, phosphorylation of Sox2 at S39 and S253, overexpression of Cyclin A and Cyclin E, knockdown of Rb,